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URAT1
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN17737 | Verinurad | 1352792-74-5 | Verinurad is an inhibitor of urate transporter with EC50 of 0.05 μM. |
CSN16305 | Lesinurad sodium | 1151516-14-1 | Lesinurad sodium is an inhibitor of URAT1 and OAT and it is also a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively. |
CSN16882 | 2-((5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid | 878672-00-5 | Lesinurad is a URAT1 inhibitor with IC50 of 3.5 µM. It acts as a transporter that regulates uric acid excretion in kidney. |
CSN11055 | Fraxin | 524-30-1 | Fraxin protects HUVECs from oxidative stress, enhances urate excretion partly by inhibiting mURAT1 or mGLUT9 in kidney of hyperuricemic mice. It is a natural product isolated and purified from the bark of Fraxinus brngeana DC.. |
CSN33678 | URAT1 inhibitor 1 | 2268720-62-1 | |
CSN75379 | Benzarone | 1477-19-6 |
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