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Flavonoids
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN16440 | Wogonin | 632-85-9 | Wogonin acts as an inhibitor of COX2 with IC50 of 46 μM without affecting COX-1 and inhibits the NF-κB pathway-mediated iNOs induction. Wogonin can be isolated from the root of scutellaria baicalensis georgi. |
CSN14293 | Warangalone | 4449-55-2 | Warangalone is a powerful inhibitor of protein kinase A isolated and purfied from the stem bark of Erythrina addisoniae, shows marked effectiveness as an anti-inflammatory on the phospholipase A(2)-induced paw edema and on the 12-O-tetradecanoylphorbol 13-acetate-induced ear edema in mice, after systemic and local administration, respectively. |
CSN19902 | Vitexicarpin | 479-91-4 | Vitexicarpin, a natural product isolated and purified from the fruits of Vitex trifolia L. var. simplicifolia Cham., can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells, and may become a potential leading drug in the therapy of prostate carcinoma. |
CSN19352 | 2-(3,4-Bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one | 7085-55-4 | Troxerutin, also known as vitamin P4, can inhibit platelet aggregation and the production of ROS. It is a flavonol isolated from Sophora japonica and used as a vasoprotective. |
CSN14606 | Thevetiaflavone | 29376-68-9 | Thevetiaflavone is a natural product isolated and purified from the herbs of Wikstroemia indica. |
CSN14278 | Tetrahydroamentoflavone | 48236-96-0 | Tetrahydroamentoflavone, a potent XO inhibitor isolated and purified from the herbs of Selaginella uncinata, exerts its antioxidant activity in vitro through metal-chelating, and radical-scavenging, and has anti-inflammatory effects. It shows in vitro cyclooxygenase (COX) inhibition activity ( an IC(50) value of 29.5 microM (COX-1) and 40.5% inhibition at 100 mg/mL (COX-2)). |
CSN16637 | Tectoridin | 611-40-5 | Tectoridin, an isoflavone, is a natural product isolated and purified from the rhizomes of belamcanda chinensis (L.) DC. with anti-inflammatory activities. |
CSN14818 | Steppogenin | 56486-94-3 | Steppogenin is a natural prodcut isolated and purified from the stems of Cudrania tricuspidata with cytotoxicity and significant tyrosinase inhibition activity. |
CSN14314 | Sideritoflavone | 70360-12-2 | Sideritoflavone is a natural product isolated and purified from the aerial parts of Stachys glutinosa. with anti-inflammatory effect , and is a selective inhibitor of lipoxygenase activity in vitro. |
CSN19422 | 7-Hydroxy-3-(4-hydroxyphenyl)-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one | 3681-99-0 | Puerarin, an isoflavones, is antagonist of 5-HT2C receptor and benzodiazepine site that can reduce anxiety symptoms associated with alcohol withdrawal. Puerarin is found in the root of radix puerariae. |
CSN19444 | 5-Hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one | 552-59-0 | Prunetin can inhibit the aldehyde dehydrogenases in liver. It is a flavonoid compound isolated from the herbs of millettia dielsiana. |
CSN14282 | Podocarpusflavone A | 22136-74-9 | Podocarpusflavone A is a DNA topoisomerase I inhibitor isolated and purified from the barks of Podocarpus macrophyllus, and is the strongest noncytotoxic non-nucleotide molecule exhibiting a specific inhibitory activity against the RNA polymerase domain of DV-NS5 and thus is promising for chemotherapy development against dengue fever. |
CSN14296 | Pedalitin | 22384-63-0 | Pedalitin is a natural mixed-type inhibitor of tyrosinase isolated and purified from the herbs of Rabdosia rubescens, and is also a competitive inhibitor of α-glucosidase. |
CSN14602 | Mulberrin | 62949-79-5 | Mulberrin can act as HIV-1 reverse transcriptase inhibitor and reduce blood sugar of type II diabetes in rats. It is purified from the root bark of morus alba L. |
CSN15664 | 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methylbut-2-en-1-yl)pyrano[2,3-f]chromen-4(8H)-one | 62596-29-6 | Morusin shows suppression of NFκB and STAT3 in many cancer cell lines including HT-29, A549, MCF-7, and MDA-MB-231. It is a flavonoid purified from the root bark of morus alba L. with antitumor activity. |
CSN18660 | 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one | 491-70-3 | Luteolin is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Kis of 15.0/6.4/13.9/11.1/9.5 μM, respectively, it is a flavonoid found in Terminalia chebula. |
CSN14311 | Licorisoflavan A | 129314-37-0 | Licorisoflavan A and licoricidin have potential for the development of host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis. |
CSN15416 | Leachianone G | 152464-78-3 | Leachianone G, a natural product isolated and purified from the roots of Sophora flavescens Ait., shows inhibitory activities against pancreatic lipase, and may be used as drug candidate to control obesity. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, and shows potent antiviral activity (IC(50) = 1.6 mg/mL). |
CSN14312 | Ladanein | 10176-71-3 | Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins. |
CSN15422 | Kushenol X | 254886-77-6 | Kushenol X is a natural product isolated and purified from the roots of Sophora flavescens Ait. exhibiting inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). |
CSN14297 | Kushenol A | 99217-63-7 | Kushenol A, a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors isolated and purified from the roots of Sophora flavescens Ait., exhibits inhibitory activity against sodium-dependent glucose cotransporter 2(SGLT2 and shows selective alpha-glucosidase inhibitory activity. |
CSN16382 | 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | 520-18-3 | Kaempferol acts as an inverse agonist that directly binds ERRα and ERRγ. It is a natural flavonol with antitumor activity. |
CSN19903 | Isoorientin | 4261-42-1 | Isoorientin is a natural product isolated and purified from the herbs of Polygonum orientale Linn. with antioxidant activity. |
CSN19464 | 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one | 489-32-7 | Icariin is a cGMP-specific PDE5 inhibitor with IC50 of 0.432 μM, 167-fold selective for PDE5 than PDE4 and exhibits multiple biological properties, including anti-inflammatory, neuroregulatory and neuroprotective activities. It is a major constituent of flavonoids from the Chinese medicinal herb Epimedium brevicornum.. |
CSN19421 | 5-Hydroxy-3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one | 529-59-9 | Genistin is a isoflavone which has a role in blocking cell cycle and inducing apoptosis. It is also a modulator of estrogen receptor. Genistin can be isolated from the seeds of glycine max (L.) merr. and used as negative control of genistein. |
CSN18651 | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one | 446-72-0 | Genistein has multiple biological functions. It can inhibit several tyrosine kinases (IC50 of 0.6 μM for EGFR), inhibits DNA topoisomerase-II and activation of PPARs. Genistein is a phytoestrogen which has selective estrogen receptor modulator properties. |
CSN14824 | Derrone | 76166-59-1 | Derrone, a natural product isolated and purified from the herbs of Cudrania tricuspidata, may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens, and is an Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids. |
CSN15117 | Dehydroglyasperin C | 199331-35-6 | Dehydroglyasperin C, a natural product isolated and purified from the roots of Glycyrrhiza uralensis Fisch, suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K. |
CSN17329 | 7-Hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one | 486-66-8 | Daidzein can act as an inhibitor of tyrosine kinase and an activator of estrogen receptor. It is inactive analogue of genistein. |
CSN15420 | Corylifol C | 775351-91-2 | Corylifol C is a natural product isolated and purified from the seeds of Psoralea corylifolia L., and a potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/mL, respectively). |
CSN14607 | Corylifol A | 775351-88-7 | Corylifol A is a phenolic compounds isolated from Psoralea corylifolia and inhibits IL-6-induced STAT3 activation and phosphorylation (IC50=0.8 μM). |
CSN15663 | Bavachin | 19879-32-4 | Bavachin, a flavonoid phytoestrogen, can activate the estrogen receptors ERα (EC50 = 320 nM) and ERβ (EC50 = 680 nM). |
CSN15665 | 5,7-Dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one | 113558-15-9 | Baohuoside I, a flavonoid, acts as an apoptosis inducer and a down-regulator of durvivin and cyclin D1 expression. It is used as an anti-cancer agent and can be isolated and purified from the roots of epimedium brevicornu Maxim. |
CSN16193 | 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid | 21967-41-9 | Baicalin, the glucuronide of baicalein, exhibits the reduction of the expression of NF-κB and effect on GABA receptor. Baicalin can be extracted from the root of astragalus membranaceus with antioxidant and anti-inflammatory activities. |
CSN15955 | (2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)chroman-4-one | 29838-67-3 | Astilbin is a flavonoid compound that can enhance NRF2 activition with anti-inflammatory properties. It could be extracted from chinese astilbe. Astilbin has been found to have significant immunosuppressive effects in recent years. |
CSN16319 | Alpinetin | 36052-37-6 | Alpinetin can act as an inhibitor of UCK2 and shows antioxidant, anticancer and antithrombotic properties. Alpinetin is mainly found in ginger plants. |
CSN15031 | Agrimonolide 6-O-β-D-glucoside | 126223-29-8 | Agrimonolide-6-O-glucopyranoside has antimicrobial activity. |
CSN19459 | 7,4'-Di-O-methylapigenin | 5128-44-9 | 7,4'-Di-O-methylapigenin, a flavonoid purified from aquilaria sinensis, can inhibit α-glucosidase, α-amylase enzymes and enhance 2-NBDG uptake in L6 cells. It has hypolipidemic effect. |
CSN19324 | 3-O-Methylquercetin | 1486-70-0 | 3-O-Methylquercetin, a natural product isolated and purified from the herbs of Croton cascarilloides with antiviral, anti-inflammatory and bronchodilating effects, is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value. 3-O-Methylquercetin also inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations. |
CSN16835 | (2R,3R)-2-(3,4,5-Trihydroxyphenyl)chromane-3,5,7-triol | 970-74-1 | (-)-Epigallocatechin is a plant secondary metabolite abundant in green tea, it can prevent conversion of unfolded native polypeptides to amyloid fibrils. |
CSN16836 | (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate | 989-51-5 | (-)-Epigallocatechin Gallate, an antioxidant, inhibits telomerase and DNA methyltransferase. It is a polyphenol flavonoid extracted from green tea. |
CSN16833 | (-)-Catechin gallate | 130405-40-2 | (-)-Catechin gallate is a natural product isolated and purified from the wood of Acacia catechu (L.F.) Willd., can enhance Fe(2+)-induced lipid peroxidation. |
CSN15641 | (+)-Gallocatechin | 970-73-0 | (+)-Gallocatechin, a natural product isolated and purified from the wood of Acacia catechu (L.F.) Willd., has moderate affinity to the human cannabinoid receptor. |
CSN16512 | (+)-Catechin | 154-23-4 | (+)-Catechin, a plant secondary metabolite, is an antioxidant flavonoid found in the bark of taxus yunnanensis with anti-atherosclerosis. |
CSN16846 | (2R,3S)-2-(3,4-Dihydroxyphenyl)chromane-3,5,7-triol xhydrate | 225937-10-0 | (+)-Catechin, a natural product isolated and purified from the herbs of Camellia sinensis, has antioxidant activity and is effective in reducing oxidative stress. |