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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN10356 | (E)-7-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one | 495-02-3 | Auraptene is a natural product isolated and purified from the peel of Poncirus trifoliata with anti-tumor and anti-oxidant activity. Auraptene-mediated activation of JNK may contribute to the production of Aβ by promoting γ-secretase activity. |
| CSN10033 | PAP-1 | 870653-45-5 | PAP-1 is a selective inhibitor of Kv1.3, voltage-gated K+ channel, it potently inhibits human T effector memory cell proliferation with EC50 of 2 nM and delayed hypersensitivity. |
| CSN10070 | Beclometasone Dipropionate | 5534-09-8 | Beclometasone dipropionate, a prodrug of beclometasone, is a glucocorticoid agonist which is used to treat rhinitis and sinusitis. |
| CSN10088 | Hydrocortisone Acetate | 50-03-3 | Hydrocortisone acetate, the acetate salt form of hydrocortisone, is a corticosteroid with anti-inflammatory and is used to decrease swelling, itching, and pain. |
| CSN10202 | Acemetacin | 53164-05-9 | Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor. |
| CSN10205 | N-(4-Hydroxyphenyl)acetamide | 103-90-2 | Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively. |
| CSN10246 | Allantoin | 97-59-6 | Allantoin is a diureide of glyoxylic acid used as a skin conditioning agent. |
| CSN10364 | Azatadine dimaleate | 3978-86-7 | Azatadine dimaleate is an inhibitor of histamine and cholinergic with IC50 of 6.5 nM and 10 nM, respectively. |
| CSN10366 | Azathioprine | 446-86-6 | Azathioprine can inhibit GTP-binding protein Rac1 activation and purine synthesis. Azathioprine is used to treat organ transplantation and autoimmune diseases. |
| CSN10380 | (S)-2-(4-Hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)chroman-4-one | 19879-30-2 | Bavachinin is an agonist of PPAR with EC50s of 4.0 µM, 8.1 µM, and 0.74 µM for α,β/δ, and γ respectively. It is a natural flavanone with anti-angiogenic effect. |
| CSN10398 | BENORILATE | 5003-48-5 | Benorylate HCl is an ester-linked codrug of aspirin with paracetamol, used as an anti-inflammatory and antipyretic medication. |
| CSN10402 | 2-(4-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic acid | 202189-78-4 | Bilastine selectively antagonizes histamine H1 receptor and it is used to treat allergic rhinoconjunctivitis and urticaria. |
| CSN10415 | Bepotastine besilate | 190786-44-8 | Bepotastine besilate is a selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7. |
| CSN21193 | Takinib | 1111556-37-6 | Takinib is a selective TAK1 inhibitor with IC50 of 9.5 nM, it can induce apoptosis in a TNF-α-dependent manner in rheumatoid arthritis (RA) and breast cancer models. |
| CSN18735 | A-1331852 | 1430844-80-6 | A1331852 is a potent and selective BCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases. |
| CSN10201 | Aceclofenac | 89796-99-6 | Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of diclofenac. |
| CSN10084 | (6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl acetate | 3801-06-7 | Fluorometholone acetate is a synthetic corticosteroid that is used to treat steroid responsive inflammatory conditions of the eye. |
| CSN10302 | Ampiroxicam | 99464-64-9 | Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. |
| CSN10040 | YM-90709 | 163769-88-8 | YM-90709 is a competitive and selective IL-5 receptor antagonist with IC50 value ranging in 0.45 - 1 mM. |
| CSN10177 | Ibuprofen L-lysine | 57469-77-9 | Ibuprofen lysine is a non-steroidal anti-inflammatory drug (NSAID). |
| CSN10076 | Chlorpheniramine maleate | 113-92-8 | Chlorpheniramine maleate is an antagonist of histamine H1 receptor with IC50 of 12 nM. |
| CSN10169 | 7,4'-Dihydroxyflavone | 2196-14-7 | 4',7-Dihydroxyflavone is a natural product isolated and purified from the heartwood of Pterocarpus marsupium, with inhibitory activities against COX-2. |
| CSN10286 | Aminoprofen | 82821-47-4 | Aminoprofen is NSAID (non-steroidal anti-inflammatory drug) and non selective COX inhibitor. Aminoprofen is used to relieve mild to moderate pain. |
| CSN10421 | β-Amyrin | 559-70-6 | beta-Amyrin, a natural cannabinoid receptors agonist isolated and purified from the stem bark of Alstonia boonei, has anti-inflammatory activity. Beta-Amyrin significantly inhibits PGE2, IL-6 secretion, and NF-κB activation in a concentration-dependent manner on LPS-induced hPBMCs. |
| CSN21088 | Withaferin A | 5119-48-2 | |
| CSN10321 | Apilimod | 541550-19-0 | Apilimod is a PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma, and can block filoviral entry and infection. It can also down-regulates both IL-12 p35 and IL-12/IL-23 p40 at the transcriptional level, and inhibits the production of both IL-12 and IL-23 cytokines. |
| CSN10365 | Azatadine | 3964-81-6 | Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively. |
| CSN10093 | Methylprednisolone succinate sodium | 2375-03-3 | 6α-Methylprednisolone 21-hemisuccinate sodium is a glucocorticoid of slightly longer half-life than that of prednisolone, and with potential uses in antiinflammatory agents. |
| CSN10215 | (R)-3-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-1-(3-phenoxypropyl)quinuclidin-1-ium bromide | 320345-99-1 | Aclidinium bromide is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). |
| CSN20319 | Complement factor D-IN-1 | 1386455-76-0 | hFD inhibitor C2 is an orally bioavailable compound and a highly potent and selective small-molecule reversible Factor D inhibitors demonstrating alternative complement pathway inhibition in vivo. |
| CSN10285 | 1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione hemiethane-1,2-diamine salt | 317-34-0 | Aminophylline is a competitive nonselective phosphodiesterase inhibitor that is used to treat airway obstruction from asthma or COPD. |
| CSN10231 | Alcaftadine | 147084-10-4 | Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. |
| CSN10355 | Auranofin | 34031-32-8 | Auranofin is a proteasomal deubiquitinase inhibitor with inhibition of the proteasome-associated deubiquitinases (DUBs) UCHL5 and USP14 rather than 20S proteasome, which is required for Auranofin-induced cytotoxicity. It selectively inhibits tumor growth in vivo and induces cytotoxicity in cancer cells from acute myeloid leukemia patients and by blocking NF-κB activation, Auranofin can attenuats the cardiac hypertrophy. |
| CSN10029 | 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione | 111025-46-8 | Pioglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARγ, EC50 = 500-600 nM) over PPAR⍺. It also a thiazolidinedione (TZD) anti-diabetic. |
| CSN18508 | A-770041 | 869748-10-7 | A-770041 is selective and orally active Src-family Lck inhibitor and is a 147 nM inhibitor of Lck(1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling. |
| CSN10308 | Anagrelide HCl | 58579-51-4 | Anagrelide HCl is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets, and also has been used in the treatment of chronic myeloid leukemia. It inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. |
| CSN10428 | Betamethasone dipropionate | 5593-20-4 | Betamethasone is the dipropionate form of betamethasone which is a glucocorticoid steroid with anti-inflammatory ability. |
| CSN18728 | Propofol | 2078-54-8 | Propofol is a short-acting medication that results in a decreased level of consciousness and lack of memory for events. |
| CSN18860 | (R)-ZINC-3573 | 2089389-15-9 | (R)-ZINC-3573 can activate endogenous MRGPRX2 in a human mast cell line and induce degranulation and calcium release. |
| CSN10309 | Metamizole Sodium Salt | 68-89-3 | Dipyrone is a non-steroidal antiinflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX. |
| CSN22382 | CRTh2 antagonist 1 | 1379445-54-1 | CRTh2 antagonist 1是 CRTh2 的拮抗剂，IC50 值为89 nM。 |
