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Inflammation/Immunology

货号 产品名 CAS号 信息
CSN10538 Phenethyl caffeate 104594-70-9 Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.
CSN10546 2-(2-(Diethylamino)ethoxy)ethyl 1-phenylcyclopentane-1-carboxylate 2-hydroxypropane-1,2,3-tricarboxylate 23142-01-0 Carβpentane citrate is a selective inhibitor of mAchR with Ki value of 76nM, also binds to serotonin 5-HT3 with Ki value of 7.9 nM and works as an agonist of the sigma-1 receptor (Ki = 10.4 nM).
CSN10595 Celecoxib 169590-42-5 Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM.
CSN10607 1,2-Dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium chloride 3895-92-9 Chelerythrine Chloride is a potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM) and competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.
CSN10664 Clemizole 442-52-4 Clemizole is an antagonist of H1 histamine receptor that can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.
CSN10668 Clobetasol propionate 25122-46-7 Clobetasol propionate is a corticosteroid with anti-inflammatory effect and is used to treat various skin disorders.
CSN10709 Sodium 5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) 15826-37-6 Disodium Cromoglycate is an antiallergic drug.
CSN10773 Deracoxib 169590-41-4 Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).
CSN10775 Desloratadine 100643-71-8 Desloratadine is an antagonist of histamine H1 receptor that is used to treat allergies.
CSN10780 Desonide 638-94-8 Desonide is a nonfluorinated corticosteroid with anti-inflammatory effect that is used for the treatment of dermatoses.
CSN10782 Dexamethasone 21-Acetate 1177-87-3 Dexamethasone Acetate is a synthetic glucocorticoid which works as a glucocorticoid receptor agonist and an interleukin receptor modulator.
CSN10793 Diclofenac Diethylamine 78213-16-8 Diclofenac diethylamine is a non-selective COX inhibitor used as a nonsteroidal anti-inflammatory drug (NSAID).
CSN10856 Doramapimod 285983-48-4 Doramapimod is a highly selective p38α MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCα/β/γ.
CSN10863 Doxofylline 69975-86-6 Doxofylline is a methylxanthine bronchodilator used to treat asthma, COPD and bronchospasm, whiel the anti-asthmatic effects are mediated primarily through inhibiting the activities of the phosphodiesterase (PDE) enzyme.
CSN10885 2-Phenylbenzo[d][1,2]selenazol-3(2H)-one 60940-34-3 Ebselen is a small-molecule capsid inhibitor of HIV-1 replication with anti-inflammatory, anti-oxidant and cytoprotective activity.
CSN10891 (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one 154598-52-4 Efavirenz is an inhibitor of wild-type HIV-1 reverse transcriptase with Ki of 2.93 nM and the IC95 of its replicative spread is 1.5 nM in cell culture.
CSN10999 Fenbufen 36330-85-5 Fenbufen is a phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
CSN11010 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid 83799-24-0 Fexofenadine is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.
CSN11027 Flumetasone 2135-17-3 Flumethasone is a corticosteroid mainly used in combination with clioquinol to treat otomycosis and otitis externa.
CSN11031 (2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-2,6b-Difluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one 67-73-2 Fluocinolone acetonide, the acetonide form of fluocinolone, is a derivative of glucocorticoid and is used for the treatment of skin disorders.
CSN11032 Fluocinonide 356-12-7 Fluocinonide is a derivative of glucocorticoid and is used for the treatment of skin disorders.
CSN11066 5-(Morpholinomethyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-one hydrochloride 3759-92-0 Furaltadone HCl is a veterinary product used for the treatment and control of salmonella infection of poultry.
CSN10917 Epinastine HCl 108929-04-0 Epinastine HCl is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
CSN11003 Fenoprofen Calcium 34597-40-5 Fenoprofen Calcium is COX-1/2 inhibitor used as an NSAID. It can also inhibit fatty acid oxidation and acts as a peroxisome proliferator.
CSN10964 Etodolac 41340-25-4 Etodolac is a non-selective inhibitor of COX with IC50 of 53.5 nM, it is a non-steroidal anti-inflammatory compound.
CSN11043 Flurandrenolide 1524-88-5 Fludroxycortide is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations.
CSN10492 Brompheniramine maleate 980-71-2 Brompheniramine maleate is an antagonist of histamine H1 receptors.
CSN10883 Ebastine 90729-43-4 Ebastine is a selective H1-histamine receptor antagonist.
CSN10548 Carbinoxamine maleate salt 3505-38-2 Carbinoxamine maleate is a blocker of histamine-H1 receptor with antihistamine and anticholinergic effects.
CSN11030 Flunixin meglumine 42461-84-7 Flunixin meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity.
CSN10695 Cortexolone 152-58-9 Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
CSN10864 Doxylamine succinate 562-10-7 Doxylamine Succinate Salt is an antihistamine which inhibits histamine H1 receptors. It can be used as a short-term sedative and anticholinergic agent.
CSN10835 Metamizole sodium hydrate 5907-38-0 Metamizole sodium is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).
CSN10554 Carnosol 5957-80-2 Carnosol, a natural product isolated and purified from the herbs of Rosmarinus officinalis L., enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. Carnosol may as an agonist of TRPA1 with an EC50 value of 12.46 µM.
CSN10909 Enprofylline 41078-02-8 Enprofylline is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator.
CSN10518 Butibufen 55837-18-8 Butibufen, is a cyclooxygenase inhibitor used to treat inflammatory and rheumatic disorders.
CSN11045 Fluticasone Propionate 80474-14-2 Fluticasone propionate is an agonist of glucocorticoid receptor (GR). It is derived from fluticasone and used to treat allergic rhinitis and asthma.
CSN10884 Ebrotidine 100981-43-9 Ebrotidine is a competitive H2-receptor antagonist (Ki= 127.5 nM) with a potent antisecretory activity and evidenced gastroprotection.
CSN10757 Decloxizine 3733-63-9 Decloxizine is a histamine 1 receptor antagonist.
CSN10950 Toll-like receptor modulator 926927-42-6 Toll-like receptor modulator is a quinazolinone-derived regulator of both Toll-like receptor and γ-secretase.
CSN10600 Cetirizine 83881-51-0 Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.
CSN11056 Frentizole 26130-02-9 Frentizole, an immunosuppressive drug, is an inhibitor of the Aβ-ABAD interaction.
CSN10783 Dexchlorpheniramine maleate 2438-32-6 Dexchlorpheniramine maleate is an antihistamine, with anticholinergic properties, used to treat allergic conditions.
CSN10969 Etoricoxib 202409-33-4 Etoricoxib is a selective COX2 inhibitor with IC50 of 1.1 ± 0.1 μM and 116 ± 8 μM for COX1.
CSN10503 Bufexamac 2438-72-4 Bufexamac is a COX inhibitor used as an anti-inflammatory agent.
CSN10640 Cilomilast 153259-65-5 Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity.
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