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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN16879 | Pimavanserin hemitartrate | 706782-28-7 | Pimavanserin Dihydroxysuccinate(2:1) is an antagonist of 5-HT2 receptor, used to treat hallucinations and psychosis in patients with Parkinson disease. |
| CSN16095 | Rilapladib | 412950-08-4 | SB-659032 is a selective and orally active inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) that is being developed for the treatment of atherosclerosis. |
| CSN16536 | TBPB | 634616-95-8 | TBPB is an allosteric M1 mAChR agonist (EC50=289 nM) that regulates amyloid processing and produces antipsychotic-like activity in rats. |
| CSN16621 | NS11394 | 951650-22-9 | NS11394 is a potent and subtype-selective GABA (A) receptor-positive modulator, possessing a functional efficacy selectivity profile of alpha(5) > alpha(3) > alpha(2) > alpha(1) at GABA (A) alpha subunit-containing receptors. |
| CSN12498 | Duloxetine | 116539-59-4 | Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). |
| CSN17330 | CB1-IN-1 | 1429239-98-4 | CB1-IN-1 is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. |
| CSN16690 | Granisetron HCl | 107007-99-8 | Granisetron HCl is an indazole-derived 5-HT3 receptor antagonist with antiemetic properties. |
| CSN16906 | (2R,4R)-APDC | 169209-63-6 | (2R,4R)-APDC is a highly potent and highly selective agonist for mGluR-2 (group II metabotropic glutamate receptors). The compound is useful for investigating the functions of metabotropic glutamate receptors in situ.(2R,4R)-APDC inhibits the NADPH-oxidase dependent ROS system.(2R,4R)-APDC is an activator of mGluR-3. |
| CSN17057 | CL-216303 Hydrochloride | 86215-36-3 | CL-216303 HCl is a dopamine transporter inhibitor and a 5-HT inhibitor potentially for the treatment of depression. |
| CSN13109 | Demoxepam | 963-39-3 | Demoxepam is a drug which is a benzodiazepine derivative. |
| CSN12580 | 7-Bromo-6-chloro-3-(3-((2S,3R)-rel-3-hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one hydrobromide | 64924-67-0 | Halofuginone hydrobromide ointment may stop the growth of Kaposi's sarcoma by stopping blood flow to the tumor. |
| CSN17050 | Eltoprazine HCl | 98206-09-8 | Eltoprazine is a serenic or antiaggressive agent as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor. |
| CSN13778 | Telcagepant | 781649-09-0 | MK-0974 is a highly potent, selective, and orally bioavailable CGRP receptor antagonist with Ki values of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors respectively, displaying > 1500-fold lower affinity for the canine and rat receptors. |
| CSN12935 | Domperidone | 57808-66-9 | Domperidone is an antagonist of dopamine D2 receptor and the IC50 value for rat D2 receptor is 13.6 nM. |
