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Neurological Disease

货号 产品名 CAS号 信息
CSN11710 N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide 73-31-4 Melatonin is a hormone which plays a role in natural sleep-wake cycle and also a ATF6 blocker.
CSN11729 Piperidolate 82-98-4 Piperidolate is a muscarinic receptor antagonist which inhibits the action of acetylcholine at postganglionic cholinergic sites.
CSN11734 Pirenzepine 2HCl 29868-97-1 Pirenzepine 2HCl is a is an anticholinergic agent and induces the dimerization of muscarinic M1 receptors, used to treat myopia, gastric and duodenal ulcers.
CSN11757 trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride 23828-92-4 Ambroxol HCl is an inhibitor of neuronal Na+ channels. It inhibits TTX-resistant and sensitive Na+ currents with IC50 of 35.2 μM (tonic)/22.5 μM (phasic block) and 100 μM, respectively.
CSN11760 (S)-N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine dihydrochloride 104632-25-9 Pramipexole 2HCl is an dopamine agonist and can inhibit multiple dopamine receptors including dopamine D2S receptor, dopamine D2L receptor, dopamine D3 receptor, and dopamine D4 receptor with respectively Ki values of 3.9, 2.2, 0.5 and 5.1 nM.
CSN11774 Procaine 59-46-1 Procaine, a benzoic acid derivative, is an anesthetic drug through targeting multiple proteins.
CSN11795 Prucalopride 179474-81-8 Prucalopride is a high-affinity 5-HT4 receptor agonist。
CSN11825 Racecadotril 81110-73-8 Racecadotril is an enkephalinase inhibitor with IC50 value of 4.5 μM, used as an antidiarrheal drug.
CSN11832 Rasagiline Mesylate 161735-79-1 Rasagiline Mesylate is an irreversible and selective MAO-B inhibitor used in early Parkinson's disease.
CSN11851 (S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate 123441-03-2 Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 μM for cholinesterase, used for the treatment of mild to moderate Alzheimer's disease and Parkinson's disease.
CSN11852 Rivastigmine tartrate 129101-54-8 Rivastigmine tartrate is an AchR inhibitor use for treatment of mild to moderate Alzheimer's disease and Parkinson's disease with elimination half-life of ‎1.5 hours.
CSN11859 Rolipram 61413-54-5 Rolipram is a selective inhibitor of phosphodiesterases PDE 4, especially the PDE 4B with IC50 of 130 nM while IC50 for PDE4D is 240 nM, it's an anti-inflammatory agent.
CSN11866 (2R,6aS,12aS)-8,9-Dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one 83-79-4 Rotenone is a proven complex I inhibitor with IC50 value of 1.7 - 2.2 μM.
CSN11878 Cutamesine 2HCl 165377-44-6 SA4503 2HCl is the 2HCl form of SA4503 which is an agonist of opioid sigma1 receptor (σ1R) with IC50 of 17.4 nM.
CSN11880 (S)-2-((4-((3-Fluorobenzyl)oxy)benzyl)amino)propanamide 133865-89-1 Safinamide is a reversible and highly selective MAO-B inhibitor with IC50 of 98 nM.
CSN11919 Sertraline HCl 79559-97-0 Sertraline HCl is a selective serotonin reuptake inhibitor (SSRI) class and inhibits 5-HT with Ki of 13 nM. It is an antidepressant.
CSN11940 Benztropine mesylate 132-17-2 Benztropine mesylate is a central muscarinic antagonist and a DAT inhibitor with IC50 of 118 nM, indicated for symptomatic relief of parkinsonism and drug-induced extrapyramidal reactions.
CSN12024 1,2,3,4-Tetrahydroacridin-9-amine hydrochloride 1684-40-8 Tacrine HCl is a parasympathomimetic reversible cholinesterase inhibitor.
CSN11812 Quetiapine hemifumarate 111974-72-2 Quetiapine Fumarate is a second-generation antipsychotic with affinity for D2, 5-HT2A, H1, alpha 1 and 5-HT1A receptors, used as an atypical antipsychotic for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
CSN11794 Protriptyline HCl 1225-55-4 Protriptyline HCl is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD.
CSN11889 Clidinium bromide 3485-62-9 Clidinium bromide is mAchR antagonist used for the symptomatic treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps.
CSN11783 Promazine HCl 53-60-1 Promazine HCl is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.
CSN11994 Succinylcholine (chloride dihydrate) 6101-15-1 Succinylcholine chloride is a nAchR which acts as a depolarizing neuromuscular blocke, used as a quaternary skeletal muscle relaxant.
CSN11830 (S)-N-(2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl)propionamide 196597-26-9 Ramelteon is a synthetic melatonin analogue working by binding to and activating melatonin receptors 1 and 2.
CSN11872 Rufinamide 106308-44-5 Rufinamide, an antiepileptic agent, is approved as adjunctive therapy for Lennox-Gastaut syndrome (LGS).
CSN12030 Tampramine 83166-17-0 Tampramine is a tricyclic antidepressant (TCA).
CSN11787 Propentofylline 55242-55-2 Propentofylline, a xanthine derivative with purported neuroprotective effects, acts as a c-AMP phosphodiesterase inhibitor, a nerve growth factor stimulator, an adenosine transport inhibitor and a non-selective adenosine receptor antagonist.
CSN11770 Primidone 125-33-7 Primidone is a pyrimidinedione derivative with anticonvulsant activity.
CSN11813 Quetiapine 111974-69-7 Quetiapine is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.
CSN11788 Propoxycaine HCl 550-83-4 Propoxycaine HCl is the HCl salt form of propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity.
CSN11907 SDZ 220-581 174575-17-8 SDZ 220-581 is a potent, competitive antagonist at the NMDA glutamate receptor subtype (pKi= 7.7).
CSN11810 Pyrithioxin 2HCl 10049-83-9 Pyrithioxin 2HCl is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.
CSN11730 Piperidolate HCl 129-77-1 Piperidolate HCl is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).
CSN11786 Propantheline bromide 50-34-0 Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.
CSN11867 (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol 99755-59-6 Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.
CSN11821 (R)-Baclofen HCl 63701-55-3 (R)-Baclofen HCl is a derivative of gamma-aminobutyric acid (GABA) primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism.
CSN11920 Setiptiline 57262-94-9 Setiptiline is a serotonin receptor antagonist.
CSN11816 Quinagolide HCl 94424-50-7 Quinagolide HCl is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor.
CSN12026 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine 101626-70-4 Talipexole is a dopamine agonist that has been proposed as an antiparkinsonian agent.
CSN11823 R121919 195055-03-9 R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
CSN11722 Pimethixene 314-03-4 Pimethixene is an antihistamine and anticholinergic agent, that is often used to treat hyperactivity, anxiety, sleep disorders, and allergy.
CSN11780 Procyclidine HCl 1508-76-5 Procyclidine HCl is an potent anti-cholinergic agent, and is also known to have NMDA antagonist properties.
CSN11807 Pyridostigmine bromide 101-26-8 Pyridostigmine Bromide is a reversible cholinesterase inhibitor to treat myasthenia gravis.
CSN11877 Carbidopa 28860-95-9 Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
CSN12031 Tamsulosin HCl 106463-17-6 Tamsulosin HCl a selective antagonist at α-1A and α-1B-adrenoceptors, used to treat the symptoms of benign prostatic hyperplasia (BPH).
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