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| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN10324 | 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one | 170729-80-3 | Aprepitant is a selective and high-affinity neurokinin-1 receptor antagonist with IC50 of 0.1 nM. |
| CSN10331 | Methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide | 300-08-3 | Arecoline hydrobromide is a mAchR receptor agonist with EC50 values of 7, 95, 11, 410, and 69 nM for M1, M2, M3, M4, and M5, respectively, a nicotinic acid-based alkaloid found in the areca nut. |
| CSN10401 | Benzamide | 55-21-0 | Benzamide, an inhibitor of poly (ADP-ribose) polymerase, is a derivative of benzoic acid. |
| CSN10476 | 3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one | 89-25-8 | Edaravone is a free radical scavenger used to help with recovery following a stroke and to treat amyotrophic lateral sclerosis (ALS). |
| CSN10483 | Bretylium tosylate | 61-75-6 | Bretylium tosylate is an antiarrhythmic agent. |
| CSN10502 | Budipine | 57982-78-2 | Budipine is an uncompetitive NMDAR antagonist used as an antiparkinson agent. |
| CSN10524 | 4-Amino-3-(4-chlorophenyl)butanoic acid | 1134-47-0 | Baclofen, a gamma-amino-butyric acid derivative, is a selective GABAB agonist with IC50 of 200 nM which used as a skeletal muscle relaxant. |
| CSN10540 | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride | 153-98-0 | Serotonin HCl is an endogenous 5-HT receptor agonist. |
| CSN10605 | 3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid | 120225-54-9 | CGS 21680 is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. |
| CSN10624 | Chlorphenoxamine | 77-38-3 | Chlorphenoxamine is an antihistamine and anticholinergic and can be used as antipruritic and antiparkinsonian agent. |
| CSN10658 | Citalopram HBr | 59729-32-7 | Citalopram Hydrobromide is a highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake. |
| CSN10663 | (R)-2-(2-((R)-1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine fumarate | 14976-57-9 | Clemastine fumarate is a selective antagonist of histamine H1 receptor with IC50 of 3 nM. |
| CSN10727 | Cyproheptadine HCl | 41354-29-4 | Cyproheptadine Hydrochloride Sesquihydrate is a serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc. |
| CSN10736 | Desvenlafaxine | 93413-62-8 | Desvenlafaxine inhibits serotonin(5-HT) and norepinephrine (NE) reuptake with Ki of 40.2 nM and 558.4 nM, respectively. |
| CSN10673 | Clomethiazole | 533-45-9 | Clomethiazole can act as an agonist of GABAA and modulator of glycine receptor. It is a sedative used in the treatment of alcohol withdrawal. |
| CSN10716 | 3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride | 6202-23-9 | Cyclobenzaprine HCl is a 5-HT2 receptor antagonist as a skeletal muscle relaxant and a central nervous system (CNS) depressant with elimination half-life of 32 hours. |
| CSN10534 | Camylofine | 54-30-8 | Camylofine is an antimuscarinic and a smooth muscle relaxant. |
| CSN10487 | Bromocriptine mesylate | 22260-51-1 | Bromocriptine mesylate is a potent dopamine D2/D3 receptoragonist, which binds D2 dopamine receptor with pKi of 8.05±0.2. |
| CSN10475 | trans-2-Phenylcyclopropanamine hemisulfate | 13492-01-8 | Tranylcypromine hemisulfate is an inhibitor of monoamine oxidase (MAO) and prostacyclin synthase, potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 < 2 μM for BHC110/LSD1). |
| CSN10479 | 2-Methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride | 21535-47-7 | Mianserin HCl is inverse agonist of H1 receptor and can be act as a psychoactive agent of the tetracyclic antidepressant. |
| CSN10656 | Cisatracurium besylate | 96946-42-8 | Cisatracurium besylate is an antagonize of AchR and inhibits neuromuscular transmission, a nondepolarizing skeletal muscle relaxant. |
| CSN10655 | Cisapride | 81098-60-4 | Cisapride is a 5-HT4 agonist which can stimulate intestinal ACh release. |
| CSN10484 | BRL-15572 2HCl | 193611-72-2 | BRL-15572 2HCl is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B and exhibiting little or no affinity for a range of other receptor types. |
| CSN10351 | Atipamezole | 104054-27-5 | Atipamezole is a synthetic competitive α2 adrenergic receptor antagonist with Ki value of 1.6 nM. |
| CSN10719 | Blonanserin | 132810-10-7 | Blonanserin is a D2/5-HT2 receptor antagonist, atypical antipsychotic. |
| CSN10448 | Bifemelane | 90293-01-9 | Bifemelane is a monoamine oxidase inhibitor being investigated for the treatment of depression. |
| CSN10383 | Bazinaprine | 94011-82-2 | Bazinaprine is a monoamine oxidase inhibitor being investigated for the treatment of depression. |
| CSN10686 | Clozapine N-oxide | 34233-69-7 | Clozapine N-oxide is a major metabolite of clozapine noted to decrease SR-2A(5-HT2 serotonin receptor) density in vitro. |
| CSN10490 | Bromopride | 4093-35-0 | Bromopride is a dopamine antagonist with prokinetic properties, widely used as an antiemetic. |
| CSN10511 | Buspirone HCl | 33386-08-2 | Buspirone HCl is an anxiolytic psychotropic drug, is used to treat generalized anxiety disorder (GAD). |
| CSN10316 | Anisodamine | 55869-99-3 | Anisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. |
| CSN10410 | Tizanidine | 51322-75-9 | Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. |
| CSN10604 | Cevimeline | 107233-08-9 | Cevimeline is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors and used in the treatment of dry mouth associated with sjogren's syndrome. |
| CSN10685 | Clozapine | 5786-21-0 | Clozapine, an antipsychotic drug, is antagonist of dopamine and other receptors used to treat schizophrenia with a Ki value of 9.5 nM for M1 receptor. |
| CSN10543 | Flupirtine | 56995-20-1 | Flupirtine is a selective neuronal potassium channel opener that also has NMDA receptor antagonist properties. |
| CSN10446 | Talipexole 2HCl | 36085-73-1 | B-HT 920 is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity. |
| CSN10440 | Bethanechol | 674-38-4 | Bethanechol is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. |
| CSN10454 | Biperiden HCl | 1235-82-1 | Biperiden HCl is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. |
| CSN10453 | Biperiden | 514-65-8 | Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. |
| CSN10698 | Corydaline | 518-69-4 | Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo. |
| CSN10491 | Bromperidol | 10457-90-6 | Bromperidol is a butyrophenone derivative, is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia. |
| CSN10315 | Aniracetam | 72432-10-1 | Aniracetam is an allosteric modulator of AMPAR which can reduce glutamate receptor desensitization and potentiate metabotropic glutamate receptor activity. |
| CSN10362 | Azaphen | 24853-80-3 | Pipofezine is a potent inhibitor of the reuptake of serotonin. |
| CSN10515 | Progabide | 62666-20-0 | Progabide is an analog and prodrug of gamma-aminobutyric acid. It is commonly used in the treatment of epilepsy with agonistic activity for both the GABAA and GABAB receptors. Progabide has been investigated for many diseases besides epilepsy, including Parkinson's disease, schizophrenia, clinical depression and anxiety disorder with varying success. |
| CSN10506 | Bulleyaconitine A | 107668-79-1 | Bulleyaconitine A is an alkaloid with analgesic and anti-inflammatory activities. It is found in Aconitum bulleyanum and used for the treatment of chronic pain and rheumatoid arthritis. |
| CSN10691 | Conduritol B epoxide | 6090-95-5 | Conduritol B epoxide is an irreversible inhibitor of acid β-glucosidase (GCase) with IC50 of 1 μM. |
| CSN10696 | (8S,9S,10R,11S,13S,14S,17S)-11-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one | 50-22-6 | Corticosterone is a steroid hormone produced in the cortex of the adrenal glands, which binds to and activates both glucocorticoid and mineralocorticoid receptors. |
| CSN50195 | A201A | 37305-78-5 |
