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Calcium Channel

Calcium Channel

货号 产品名 CAS号 信息
CSN18679 Zonisamide 68291-97-4 Zonisamide, a 1,2 benzisoxazole derivative, is developed as an antiepileptic drug.
CSN18390 Zonisamide sodium 68291-98-5 Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug.
CSN20381 Ulixacaltamide 1199236-64-0 Z944 is a T-type calcium channel antagonist potentially for the treatment of pain. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats.
CSN16652 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride 152-11-4 Verapamil HCl is a phenylalkylamine class L-type calcium channel blocker.
CSN16574 trans-ACPD 67684-64-4 trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons.
CSN16381 (11S,31S)-16,36,37,54-Tetramethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphane 518-34-3 Tetrandrine, a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker that inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
CSN16709 Tetracaine HCl 136-47-0 Tetracaine HCl is a potent local anaesthetic and a channel function allosteric inhibitor.
CSN11934 1-(2-(4-Methoxyphenyl)-2-(3-(4-methoxyphenyl)propoxy)ethyl)-1H-imidazole hydrochloride 130495-35-1 SKF-96365 HCl is a transient receptor potential canonical type (TRPC) channel blocker, also bolcks voltage-gated Ca2+ channels and potassium channels.
CSN13104 Ranolazine 95635-55-5 Ranolazine inhibits calcium uptake via the sodium/calcium channel, is used to treat chronic angina.
CSN20527 Pinaverium bromide 53251-94-8 Pinaverium bromide acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel.
CSN19446 Penfluridol 26864-56-2 Penfluridol, a T-type calcium channel blocker, is a highly potent, first generation diphenylbutylpiperidine antipsychotic.
CSN15973 NP118809 41332-24-5 NP-118809 is a potent N-type calcium channel blocker with IC50 of 0.11 μM, showing good selectivity over L-type calcium channels.
CSN18785 Norverapamil HCl 67812-42-4 Norverapamil HCl is a calcium channel blocker, it is the main active metabolite of verapamil.
CSN16645 (1S,2S)-2-(2-((3-(1H-Benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl cyclopropanecarboxylate dihydrochloride 357400-13-6 NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker, displaying IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.
CSN12653 Nitrendipine 39562-70-4 Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.
CSN17095 Nisoldipine 63675-72-9 Nisoldipine is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.
CSN12874 3-Isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 66085-59-4 Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.
CSN11560 5-Isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 75530-68-6 Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.
CSN11400 Nicardipine 55985-32-5 Nicardipine is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
CSN11401 Nicardipine HCl 54527-84-3 Nicardipine HCl is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
CSN19021 Suvecaltamide 953778-58-0 MK-8998 is a potent and selective antagonist of the T-typecalcium channel.
CSN19022 Mirogabalin 1138245-13-2 Mirogabalin is a preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS.
CSN11438 Mibefradil 116644-53-2 Mibefradil is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying
CSN11439 Mibefradil 2HCl 116666-63-8 Mibefradil 2HCl is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying
CSN11358 Manidipine 89226-50-6 Manidipine is a calcium channel blocker that is used clinically as an antihypertensive.
CSN11359 Manidipine Dihydrochlorid 89226-75-5 Manidipine 2HCl is a L/T-type calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.
CSN16682 Lomerizine 2HCl 101477-54-7 Lomerizine 2HCl is an L- and T-type calcium channel blocker used in the treatment of migraine.
CSN11284 Lercanidipine 100427-26-7 Lercanidipine is a calcium channel blocker of the dihydropyridine class.
CSN11285 Lercanidipine HCl 132866-11-6 Lercanidipine HCl is a L-type calcium channel blocker, used in the treatment of hypertension.
CSN11261 Lacidipine 103890-78-4 Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.
CSN11235 3-Isopropyl 5-methyl 4-(benzo[c][1,2,5]oxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 75695-93-1 Isradipine is a potent L-type calcium channel selective blocker with an IC50 of 34±8 μM.
CSN11184 Ibutilide fumarate 122647-32-9 Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm.
CSN20010 2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one 499-44-5 Hinokitiol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. It can partially mimic the function of missing protein transporters of iron, and possibly other ions, may have potential in treating human diseases.
CSN17796 GV-58 1402821-41-3 GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 μM for N-type/P-Q-type Ca2+ channel and 20-fold less potent CDK inhibitor activity.
CSN19430 Fendiline HCl 13636-18-5 Fendiline HCl is a nonselective calcium channel blocker.
CSN16302 Efonidipine 111011-63-3 Efonidipine is a dual T-type and L-type calcium channel blocker (CCB).
CSN17471 Efonidipine HCl 111011-53-1 Efonidipine HCl is a dual T-type and L-type calcium channel blocker (CCB).
CSN16732 Econazole nitrate 24169-02-6 Econazole nitrate is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.
CSN17111 Dantrolene sodium 14663-23-1 Dantrolene sodium is an inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm.
CSN12960 Clevidipine 167221-71-8 Clevidipine is a short-acting dihydropyridine calcium channel antagonist with IC50 of 7.1 nM, it's under development for treatment of perioperative hypertension.
CSN18644 (S)-(-)-Bay-K-8644 98625-26-4 Bay-K-8644 (S)-(-)- is an agonist of L-type Ca2+ channel. Bay-K-8644 (S)-(-)- activates Ba2+ currents (IBa) (EC50=32 nM).
CSN18645 (R)-(+)-Bay-K-8644 98791-67-4 Bay-K-8644 (R)-(+)- is a calcium channel inhibitor. Bay-K-8644 (R)-(+)- inhibits Ba2+ currents (IBa) (IC50=975 nM).
CSN19219 Bay K 8644 71145-03-4 Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
CSN12852 Barnidipine HCl 104757-53-1 Barnidipine HCl is a calcium-channel blocker.
CSN16791 Amlodipine maleate 88150-47-4 Amlodipine Maleate is a long-acting calcium channel blocker.
CSN16790 Amlodipine 88150-42-9 Amlodipine is a long-acting calcium channel blocker used to lower blood pressure and prevent chest pain.
CSN13575 Amlodipine Besylate 111470-99-6 Amlodipine Besylate is a long-acting calcium channel blocker used to lower blood pressure and prevent chest pain.
CSN17606 ABT-639 1235560-28-7 ABT-639 is a peripherally acting, selective T-type Ca2+ channel blocker.
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