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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN16643 | LY2979165 | 1311385-32-6 | LY2979165 is a mGlu2 agonist, a drug candidate drug used to treat bipolar disorder. |
CSN16651 | 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one | 120014-06-4 | Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively, a medication used to treat Alzheimer's disease. |
CSN16705 | Dapoxetine HCl | 129938-20-1 | Dapoxetine HCl is an inhibitor of serotonin reuptake. It can treat premature ejaculation. |
CSN16772 | Phenytoin sodium | 630-93-3 | Phenytoin sodium is a stabilizer of inactive voltage-gated sodium channel. |
CSN16779 | 7-((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid | 72797-41-2 | Tianeptine is a unique tricyclic antidepressant, in contrast to SSRIs, which can increase serotonin uptake in the brain and reduce stress-induced atrophy of neuronal dendrites. |
CSN16789 | Dibucaine | 85-79-0 | Cinchocaine is amide type local anesthetic that is generally used for surface anesthesia. |
CSN16795 | Tetracaine | 94-24-6 | Tetracaine can interfer the entry of sodium ions into nerve cells and used as a topical local anesthetic. |
CSN16796 | 3-(Aminocarbonyl)pyridine | 98-92-0 | Nicotinamide can act as an inhibitor of sirtuins and it is the active component of NAD and NADP. |
CSN16886 | Ramosetron HCl | 132907-72-3 | Ramosetron HCl is a potent and selective 5-HT3 receptor antagonist for the treatment of nausea and vomiting. |
CSN16934 | P7C3 | 301353-96-8 | P7C3 is a brain-penetrant NAMPT activator with proneurogenic and neuroprotective effect. |
CSN16786 | Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate | 78755-81-4 | Flumazenil is a non-selective antagonist of benzodiazepine towards α1, α2, α3 or α5-containing GABAA receptors. |
CSN16682 | Lomerizine 2HCl | 101477-54-7 | Lomerizine 2HCl is an L- and T-type calcium channel blocker used in the treatment of migraine. |
CSN16737 | Oxcarbazepine | 28721-07-5 | Oxcarbazepine is a voltage-gated sodium channel blocker with IC50 of 160 μM and it is used for the treatment of partial seizure. |
CSN16724 | Clomipramine HCl | 17321-77-6 | Clomipramine HCl is a dibenzazepine-derived 5-HT reuptake inhibitor and a tricyclic antidepressant. |
CSN16709 | Tetracaine HCl | 136-47-0 | Tetracaine HCl is a potent local anaesthetic and a channel function allosteric inhibitor. |
CSN16627 | VU0152100 | 409351-28-6 | VU 0152100 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93 nM. |
CSN16622 | JTC-801 | 244218-51-7 | JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, and weakly inhibits receptors δ, κ, and μ. |
CSN16855 | (±)-Huperzine A | 120786-18-7 | (±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs of Lycopodium serratum, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). |
CSN16735 | Nicergoline | 27848-84-6 | Nicergoline is a non-selective alpha-adrenergic receptor antagonist which can decrease vascular resistance and increase arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. |
CSN16841 | (7S,7aR,14S,14aS)-Tetradecahydro-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine | 90-39-1 | (-)-Sparteine is a class 1a antiarrhythmic agent and a sodium channel blocker. |
CSN16680 | topride HCl | 122892-31-3 | Itopride HCl is a D2 antagonist and an AChE inhibitor with an IC50 value of 2.04±0.27 μM. It is a prokinetic benzamide derivative unlike domperidone. |
CSN16775 | Atracurium besylate | 64228-81-5 | Atracurium besylate is a non-depolarizing neuromuscular blocking agent with short duration of action. |
CSN16653 | Olanzapine | 132539-06-1 | Olanzapine is a multiple-target antagonist for 5-HT2A receptors and D2 dopamine receptors, as well as muscarinic M3 receptor. |
CSN16711 | Agomelatine | 138112-76-2 | Agomelatine is a melatonin structurely similar 5-HT2C receptor antagonist as well as a potent melatonin receptor agonist, used to treat major depressive disorder. |
CSN16669 | Gabapentin HCl | 60142-95-2 | Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain. |
CSN16659 | CTEP | 871362-31-1 | CTEP is a selective allosteric mGluR5 antagonist with IC50 value of 2.2 nM. |
CSN16751 | Intepirdine | 607742-69-8 | SB-742457 is a selective 5-HT6 receptor antagonist with Ki value of 1.4 nM, showing potential cognition, memory, and learning-enhancing effects. |
CSN16715 | Pancuronium dibromide | 15500-66-0 | Pancuronium dibromide is a competitive nAchR antagonist, causing skeletal muscle relaxation and paralysis through competitively binding to the nicotinic receptor at the neuromuscular junction. |
CSN16726 | Tegaserod maleate | 189188-57-6 | Tegaserod Maleate is a potent full agonist at 5-HT4 receptors with an EC50 value of 7 nM, used to treat irritable bowel syndrome associated with constipation and chronic constipation. |
CSN16954 | Xanomeline oxalate | 141064-23-5 | Xanomeline Oxalate is a selective M1 muscarinic receptor agonist. |
CSN16914 | Nav1.7 inhibitor | 1355631-24-1 | Nav1.7 inhibitor is a sulfonamide derivative with potent Nav1.7 inhibition activity. |
CSN16747 | 2-(1H-Imidazol-4-yl)ethan-1-amine | 51-45-6 | Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. |
CSN16753 | LX-1031 | 945976-76-1 | LX1031 is an oral, small molecule tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin(5-HT) synthesis peripherally. |
CSN16686 | Ondansetron HCl | 99614-01-4 | Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy. |
CSN16969 | Telotristat ethyl | 1033805-22-9 | LX1606 is an orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production. |
CSN16745 | Adiphenine HCl | 50-42-0 | Adiphenine HCl is a nicotinic receptor inhibitor with IC50 of 15 μM, used as an antispasmodic drug. |
CSN16693 | Granisetron | 109889-09-0 | Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. |
CSN16865 | NBI-98782 | 85081-18-1 | NBI-98782 is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.97 nM. |
CSN16591 | CP-809101 HCl | 1215721-40-6 | CP-809101 HCl is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively. |
CSN16899 | Phenelzine | 51-71-8 | Phenelzine is a non-selective and irreversible monoamine oxidase inhibitor (MAOI), used as an antidepressant and anxiolytic. |
CSN16799 | WAY-100635 | 162760-96-5 | WAY-100635 is a potent and selective 5-hydroxytryptamine1A antagonist with an IC50 of 0.95 ± 0.12 nM for 5-HT. |
CSN16857 | QNZ46 | 1237744-13-6 | QNZ46 is a noncompetitive and voltage-independent GluN2C/GluN2D-selective NMDA antagonist with IC50 values of 3, 6, 229 μM for GluN2D, GluN2C, GluN2A, respectively. |
CSN16936 | S1RA | 878141-96-9 | S1RA is a potent and selective sigma-1 receptor (σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM). |
CSN16798 | GW791343 2HCl | 1019779-04-4 | GW791343 2HCl is a P2X7 allosteric modulator exhibiting species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). |
CSN16688 | Tamsulosin | 106133-20-4 | Tamsulosin is an α1 adrenergic receptor blocker used to treat symptomatic benign prostatic hyperplasia (BPH), chronic prostatitis, and to help with the passage of kidney stones. |
CSN16826 | SB-674042 | 483313-22-0 | SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM) exhibiting 100-fold selectivity for OX1 over OX2 receptors. |
CSN16823 | HC-030031 | 349085-38-7 | HC-030031 is a blocker of TRPA1 channel that exhibits antagonistic effect on AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively. |