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COX

COX

货号 产品名 CAS号 信息
CSN12344 Valdecoxib 181695-72-7 Valdecoxib is a potent COX inhbitor that selectively inhibitors COX-2 with IC50 of 5 nM.
CSN12172 Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate 67330-25-0 Ufenamate is a COX inhibitor, used as a topical analgesic.
CSN12136 Tribenoside 10310-32-4 Tribenoside is a vasoprotective and a mixture of the α- und β-anomers.
CSN17272 Tolmetin sodium dihydrate 64490-92-2 Tolmetin sodium is a non-steroidal anti-inflammatory agent (NSAID) with antioxidant and neuroprotective properties.
CSN12107 2-((3-Chloro-2-methylphenyl)amino)benzoic acid 13710-19-5 Tolfenamic acid is a selective COX2 inhibitor with IC50 of 13.49 μM, it's a non-steroidal anti-inflammatory drugs (NSAIDs).
CSN12050 Tenoxicam 59804-37-4 Tenoxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
CSN12016 Sulindac 38194-50-2 Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) and is thought to act on enzymes COX-1 and COX-2, inhibiting prostaglandin synthesis.
CSN12396 SC-58125 162054-19-5 SC 58125 is a selective, time-dependent, and irreversible cyclooxygenase-2 (Cox-2) inhibitor that displays anti-inflammatory properties.
CSN11226 4-Isopropylantipyrine 479-92-5 Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.
CSN12646 Piroxicam 36322-90-4 Piroxicam is a selective COX1 inhibitor with anti-inflammatory effects.
CSN12368 Parecoxib Sodium 198470-85-8 Parecoxib Sodium, a water-soluble and injectable prodrug of valdecoxib, is a COX2 inhibitor used for the short-term treatment of postoperative pain in adults.
CSN12602 3-(4,5-Diphenyloxazol-2-yl)propanoic acid 21256-18-8 Oxaprozin is a COX inhibitor with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, it's a NSAID used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis.
CSN11586 NS-398 123653-11-2 NS-398 is a selective inhibitor of COX2 with IC50s of 75 and 1.77 μM for human recombinant COX1 and 2 respectively.
CSN11614 Nimesulide 51803-78-2 Nimesulide is a COX2 selective inhibitor with IC50 of 26 μM.
CSN11540 Nepafenac 78281-72-8 Nepafenac is a selective COX2 inhibitor and is prodrug of amfenac used in the treatment of pain and inflammation associated with cataract surgery.
CSN12605 (S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid 22204-53-1 Naproxen is a COX inhibitor for COX1/2 with IC50 of 8.7 and 5.2 μM, respectively.
CSN11523 Sodium (S)-2-(6-methoxynaphthalen-2-yl)propanoate 26159-34-2 Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.
CSN11503 4-(6-Methoxynaphthalen-2-yl)butan-2-one 42924-53-8 Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) and its active metabolite inhibits the COX.
CSN10835 Metamizole sodium hydrate 5907-38-0 Metamizole sodium is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).
CSN11372 Mefenamic Acid 61-68-7 Mefenamic Acid is an inhibitor of COX2 with anti-inflammatory properties, it's a non-steroidal anti-inflammatory agent.
CSN11367 Sodium 2-((2,6-dichloro-3-methylphenyl)amino)benzoate 6385-02-0 Meclofenamate Sodium is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea.
CSN11337 Loxoprofen 68767-14-6 Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) and propionic acid derivative.
CSN11332 Lornoxicam 70374-39-9 Lornoxicam is a COX inhibitor with IC50 of 5 nM and 8 nM for COX1 and 2 respectively. It's a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of various types of pain.
CSN11253 2-Amino-2-(hydroxymethyl)propane-1,3-diol 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate 74103-07-4 Ketorolac is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.
CSN11252 2-(3-Benzoylphenyl)propanoic acid 22071-15-4 Ketoprofen is a dual COX1/2 inhibitor with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively, and used as a nonsteroidal anti-inflammatory drug (NSAID) to treat arthritis-related inflammatory pains.
CSN11203 3,7,11-Trimethyldodeca-2,6,10-trien-1-yl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate 85801-02-1 Indometacin farnesil is a prodrug of the non-steroidal anti-inflammatory drug indometacin.
CSN10177 Ibuprofen L-lysine 57469-77-9 Ibuprofen lysine is a non-steroidal anti-inflammatory drug (NSAID).
CSN11183 2-(4-Isobutylphenyl)propanoic acid 15687-27-1 Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively, and is used for pain relief, fever reduction and for reducing swelling.
CSN11122 Guacetisal 55482-89-8 Guacetisal is a drug that has been used to treat inflammatory respiratory diseases.
CSN11030 Flunixin meglumine 42461-84-7 Flunixin meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity.
CSN11003 Fenoprofen Calcium 34597-40-5 Fenoprofen Calcium is COX-1/2 inhibitor used as an NSAID. It can also inhibit fatty acid oxidation and acts as a peroxisome proliferator.
CSN10999 Fenbufen 36330-85-5 Fenbufen is a phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
CSN10969 Etoricoxib 202409-33-4 Etoricoxib is a selective COX2 inhibitor with IC50 of 1.1 ± 0.1 μM and 116 ± 8 μM for COX1.
CSN10964 Etodolac 41340-25-4 Etodolac is a non-selective inhibitor of COX with IC50 of 53.5 nM, it is a non-steroidal anti-inflammatory compound.
CSN10874 Droxicam 90101-16-9 Droxicam is a non-steroidal anti-inflammatory drug of the oxicam class. As a prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
CSN10309 Metamizole Sodium Salt 68-89-3 Dipyrone is a non-steroidal antiinflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX.
CSN10793 Diclofenac Diethylamine 78213-16-8 Diclofenac diethylamine is a non-selective COX inhibitor used as a nonsteroidal anti-inflammatory drug (NSAID).
CSN10773 Deracoxib 169590-41-4 Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).
CSN11951 Diclofenac potassium 15307-81-0 CGP 45840B is a non-selective reversible and competitive inhibitor of COX, used as an anti-inflammatory drug and an analgesic agent.
CSN10595 Celecoxib 169590-42-5 Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM.
CSN10518 Butibufen 55837-18-8 Butibufen, is a cyclooxygenase inhibitor used to treat inflammatory and rheumatic disorders.
CSN10503 Bufexamac 2438-72-4 Bufexamac is a COX inhibitor used as an anti-inflammatory agent.
CSN10398 BENORILATE 5003-48-5 Benorylate HCl is an ester-linked codrug of aspirin with paracetamol, used as an anti-inflammatory and antipyretic medication.
CSN10302 Ampiroxicam 99464-64-9 Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
CSN10286 Aminoprofen 82821-47-4 Aminoprofen is NSAID (non-steroidal anti-inflammatory drug) and non selective COX inhibitor. Aminoprofen is used to relieve mild to moderate pain.
CSN10205 N-(4-Hydroxyphenyl)acetamide 103-90-2 Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively.
CSN10202 Acemetacin 53164-05-9 Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
CSN10201 Aceclofenac 89796-99-6 Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of diclofenac.
CSN10169 7,4'-Dihydroxyflavone 2196-14-7 4',7-Dihydroxyflavone is a natural product isolated and purified from the heartwood of Pterocarpus marsupium, with inhibitory activities against COX-2.
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